Prostaglandin synthesis and metabolism in the human uterus and midtrimester fetal tissues
- 1 July 1980
- journal article
- research article
- Published by Bioscientifica in Reproduction
- Vol. 59 (2) , 525-529
- https://doi.org/10.1530/jrf.0.0590525
Abstract
Prostaglandin (PG) synthesis and metabolism were studied in human fetal kidney, lung, small intestine, heart, brain and liver (gestational ages: 10, 12, 14, 18 and 23 wk) and pregnant uterus (4-40 wk of pregnancy). PG synthesis was increased in the myometrium during pregnancy; the capacity of metabolism did not change. PG synthesis increased in lung and kidney (4-fold), brain (20-fold) and small intestine (2-fold) but not in heart or liver. Metabolic activity increased in the fetal kidney and lung.This publication has 10 references indexed in Scilit:
- Effect of beta-mimetic isoxsuprine on prostaglandin biosynthesis in pregnant human myometrium in vitroLife Sciences, 1978
- PRODUCTION OF THROMBOXANE B2 BY INTRA-UTERINE TISSUES FROM LATE PREGNANT RHESUS MONKEYS (MACACA MULATTA) IN VITROJournal of Endocrinology, 1978
- THE METABOLISM OF PROSTAGLANDIN E2 BY TISSUES FROM THE HUMAN UTERUS AND FOETO-PLACENTAL UNITActa Endocrinologica, 1978
- TRIAL OF PROSTAGLANDIN-SYNTHETASE INHIBITORS IN PRIMARY DYSMENORRHŒAThe Lancet, 1978
- CORRELATION BETWEEN THE CONCENTRATIONS OF PROSTAGLANDIN DEHYDROGENASE AND PROGESTERONE IN THE EARLY HUMAN PLACENTAJournal of Endocrinology, 1978
- Experimental criteria for evaluating prostaglandin biosynthesis and intrinsic functionBiochemical Pharmacology, 1977
- Prostaglandin biosynthesis and catabolism in the developing fetal sheep kidneyProstaglandins, 1977
- Prostaglandin biosynthesis and catabolism in the developing fetal sheep lungProstaglandins, 1977
- Metabolism of Prostaglandin F2α in Early Human Placenta in vitroHormone Research, 1977
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951