Resonance Raman spectra for flavin derivatives modified in the 8-position
- 1 November 1981
- journal article
- research article
- Published by American Chemical Society (ACS) in Biochemistry
- Vol. 20 (23) , 6734-6739
- https://doi.org/10.1021/bi00526a032
Abstract
Spontaneous resonance Raman or resonance-enhanced AC-coupled inverse Raman spectra were obtained for 8-mercaptoriboflavin, 8-(dimethylamino)riboflavin, 8-hydroxyriboflavin and 8-aminoriboflavin all free in solution. These Raman spectra were all similar to one another and markedly different from that of riboflavin. In addition, the Raman spectra of 8-mercaptoflavin bound to the apoproteins of [brewer''s yeast] old yellow enzyme, [Aspergillus niger] glucose oxidase and [Mycobacterium smegmatis] L-lactate oxidase were determined. The Raman spectra of these protein-bound flavins were distinctly different from both those of the above 8-substituted riboflavins and that of riboflavin. An argument is presented in favor of assigning a quinonoid electronic structure to these protein-bound flavins.This publication has 20 references indexed in Scilit:
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