Characterization of benzodiazepine drugs by ion mobility spectrometry
- 15 February 1989
- journal article
- research article
- Published by American Chemical Society (ACS) in Analytical Chemistry
- Vol. 61 (4) , 343-349
- https://doi.org/10.1021/ac00179a012
Abstract
Note: In lieu of an abstract, this is the article's first page.This publication has 5 references indexed in Scilit:
- Photoionization in air with ion mobility spectrometry using a hydrogen discharge lampAnalytical Chemistry, 1986
- Microprocessor Controlled Chemical Detection And Alarm System Based On Ion Mobility SpectrometryOptical Engineering, 1985
- Continuous detection of hydrazine and monomethylhydrazine using ion mobility spectrometryAnalytical Chemistry, 1985
- Trace analysis of benzodiazepine drugs in blood using deactivated amberlite XAD-7 porous polymer beads and silica capillary column gas chromatography with electron-capture detectionJournal of Chromatography A, 1984
- Four benzodiazepine radioimmunoassays are described, the most sensitive of which can detect sub-therapeutic levels of bromazepam, chlordiazepoxide, clobazam, demoxepam, desalkylflurazepam, desmethyldiazepam, diazepam, flunitrazepam, lorazepam, medazepam, nitrazepam, oxazepam, prazepam, temazepam and triazolam. The standard curve for diazepam has a concentration range of 0–2·5 ng ml The assay is particularly applicable to blood samples of forensic interest that may be haemolysed or decomposing. A 75 μI sample is required. The antiserum and [3 H]flunitrazepam used are commercially availableJournal of Pharmacy and Pharmacology, 1980