Abstract
Diarrhea is a well-recognized complication of ampicillin therapy, with 5 patients reported to have pseudomembranous colitis. Although colitis is now recognized as a frequent complication of particular antibiotic usage, only 1 such case was reported previously to be associated with arthritis. The 1st case of arthritis associated with ampicillin colitis is reported and compared with the previous case of clindamycin-associated arthritis and colitis and with previous cases of ampicillin colitis.

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