An Efficient Method for the Iodination of C5-Position of Dialkoxy Pyrimidines and Uracil Bases1,2
- 1 June 1988
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 18 (8) , 855-867
- https://doi.org/10.1080/00397918808057855
Abstract
N-Iodosuccinimide in trifluoroacetic acid and trifluoroacetic anhydride was found to be an excellent reagent for the conversion of 2,4-dialkoxy pyrimidines to 2,4-dialkoxy-5-iodopyrimidines. Iodination at C5-position of uracil and its derivatives was also accomplished with the above reagent.Keywords
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