Changes in the Metabolism of Biogenic Amines in Alcoholism—Especially Regarding CSF Monoamine Metabolites and Serum DBH Activity

Abstract
Concentrations of the major metabolites of biogenic amines in cerebrospinal fluid and activity of serum dopamine-β-hydroxylase in abstinent alcoholics were measured, suggesting that withdrawal symptoms of alcoholics were based on the abnormality of serotonin and dopamine metabolism in the body.