Demyelinating Diseases

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Abstract
Multiple SclerosisEpidemiologyThe aim of numerous epidemiologic investigations has been to uncover possible etiologic factors. A summary of the earlier surveys carried out in Europe and those in this country before 1954 is contained in the work by McAlpine, Compston and Lumsden.8 Multiple sclerosis has a world-wide distribution, but its incidence appears to be quite uneven. Statistical investigations have increased during the past decade, though reliable surveys for areas below the equator are sparse. In the northern hemisphere, on the American continent, the disease occurs more frequently in the northern latitudes,135 , 136 the incidence and prevalence rates being three times . . .