Abstract
Wistar, Sprague-Dawley and Fischer rats were tested for general activity levels and for three different types of avoidance learning. No strain differences were observed for general activity or for the number of trials to learn a conditioned avoidance response (CAR) in the one-way shuttle box. The Fischer strain avoided shock more than the Wistar strain which in turn avoided shock more than the Sprague-Dawley strain during the acquisition of the CAR and nondiscriminated avoidance response in the two-way shuttle box.