Synthesis of Escherichia coli carbomoylphosphate synthetase initiates at a UUG codon
- 1 July 1985
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 150 (1) , 111-115
- https://doi.org/10.1111/j.1432-1033.1985.tb08995.x
Abstract
The ribosome binding region of the messenger RNA for the Esherichia coli car A gene contains two adjacent putative translational start codons, UUG and AUU, both of them unusual. By Edman degradation and mass spectrometry of purified car A protein, we show that only UUG is used in vivo. Translation initiation at UUG in car A appears about half as efficient as at AUG in lacZ.This publication has 30 references indexed in Scilit:
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