Placental Transfer of Calcium45 in the Rat

Abstract
Calcium45 administered orally to pregnant rats was found to cross the placenta and deposit in the fetus at all stages of gestation studied, from the 14th to the 22nd day. The amount of labeled calcium transferred from dam to fetus in a given length of time after administration increased with increasing fetal age. A study of Ca45 transfer as a function of time after isotope administration revealed that in one-half hour an appreciable amount of the orally administered isotope had been absorbed and transferred to the fetus. The findings indicate that a part of the calcium transferred to the fetus must have been derived from calcium previously stored in the maternal skeleton.

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