Mechanism Whereby Renin Increases the Rate of T-1824 Disappearance From the Circulation of Rabbits

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Abstract
Investigations were carried out to determine whether or not renin has any effect on pathways other than the glomerular capillary wall for the escape of dyed protein from the blood stream. The bulk of the evidence presented points to the conclusion that renin infusion results in a significant increase in capillary permeability towards labeled protein in general and has some small influence on reticulo-endothelial activity. Studies with angiotonin infusion suggest that this substance, rather than renin, is responsible for the altered dye disappearance rate.

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