Cytopathogenic Effects of Hemadsorption Virus Type I.

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Abstract
Time-lapse phase-contrast, cinemicrography of hemadsorption virus type I infected HeLa cells has shown that approximately 12 hours after infection multi-nucleated cells develop and through a process of coalescence of cytoplasm of adjacent cells, increase rapidly in size, until hundreds of nuclei are included in a single cell. These membrane changes precede by many hours observable nuclear or mitochondrial changes.