EFFECTS OF TOPICAL 1-EPINEPHRINE AND DIPIVALYL EPINEPHRINE ON INTRA-OCULAR PRESSURE AND PUPIL SIZE IN NORMOTENSIVE AND GLAUCOMATOUS BEAGLE
- 1 January 1978
- journal article
- research article
- Vol. 39 (1) , 83-86
Abstract
Dipivalyl epinephrine and l-epinephrine were evaluated in various concentrations in normotensive and glaucomatous beagles. In higher concentrations, both drugs produced significant lowering of intraocular pressure. Mydriasis and some local irritation occurred. The hypotony after drug administration tended to be greater in glaucomatous than in normotensive beagles. The glaucomatous beagle may be a valuable biomedical model in the investigation of various pharmacologic substances.This publication has 7 references indexed in Scilit:
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