Two Outbreaks of Multidrug-Resistant Salmonella Serotype Typhimurium DT104 Infections Linked to Raw-Milk Cheese in Northern California

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Abstract
Salmonella causes an estimated 800,000 to 4 million human infections each year in the United States,1 approximately 25% of which are serotype Typhimurium.2 Recent national surveillance data of antimicrobial resistance patterns show that a new multidrug-resistant strain of Salmonella Typhimurium is emerging.3 In 1990, less than 1% of isolates were resistant to ampicillin, chloramphenicol, streptomycin sulfate, sulfonamides, and tetracycline, a distinct 5-drug resistance pattern, but by 1996, 34% of isolates showed this pattern.