An immunoglobulin deletion mutant with implications for the heavy-chain switch and RNA splicing
- 1 August 1980
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 286 (5774) , 669-675
- https://doi.org/10.1038/286669a0
Abstract
The [mouse] IF2 immunoglobulin mutant is a DNA deletion of 1 coding segment and large sections of the flanking intervening sequences. The deletion results in a new splicing pattern, and starts in a DNA region containing tandemly repeated sequences which may carry H-chain class switch signals.Keywords
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