Neurotoxic Mechanisms Caused by the Alzheimer's Disease-linked Swedish Amyloid Precursor Protein Mutation
Open Access
- 1 July 2003
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 278 (30) , 28294-28302
- https://doi.org/10.1074/jbc.m212265200
Abstract
No abstract availableKeywords
This publication has 78 references indexed in Scilit:
- Mammalian APH-1 Interacts with Presenilin and Nicastrin and Is Required for Intramembrane Proteolysis of Amyloid-β Precursor Protein and NotchPublished by Elsevier ,2002
- PEN-2 Is an Integral Component of the γ-Secretase Complex Required for Coordinated Expression of Presenilin and NicastrinPublished by Elsevier ,2002
- Mature Glycosylation and Trafficking of Nicastrin Modulate Its Binding to PresenilinsPublished by Elsevier ,2002
- Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activityNature, 1999
- β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACEScience, 1999
- The Proteolytic Fragments of the Alzheimer's Disease-associated Presenilin-1 Form Heterodimers and Occur as a 100–150-kDa Molecular Mass ComplexJournal of Biological Chemistry, 1998
- Amyloid β-Protein and the Genetics of Alzheimer's DiseaseJournal of Biological Chemistry, 1996
- REVIEWThe Gene Defects Responsible for Familial Alzheimer's DiseaseNeurobiology of Disease, 1996
- Mutations associated with a locus for familial Alzheimer's disease result in alternative processing of amyloid beta-protein precursorPublished by Elsevier ,1994
- Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's diseaseNature, 1991