ANTIGENICITY OF HUMAN CHORIONIC GONADOTROPHIN PREPARATIONS IN MEN
- 1 May 1982
- journal article
- research article
- Published by Wiley in Clinical Endocrinology
- Vol. 16 (5) , 483-488
- https://doi.org/10.1111/j.1365-2265.1982.tb02762.x
Abstract
The antigenicity of HCG was tested in twenty‐three young healthy men receiving two different HCG preparations (A and B). Each subject received 5000 i.u. HCG intramuscularly daily for three consecutive days, followed by another course, 3 weeks later, of 5000 i.u. HCG injections daily for 3 days. Two of the fifteen subjects treated with preparation A developed HCG antibodies in response to the HCG injections. The results show that although HCG is of human origin and also occurs normally in men, it may induce antibody formation even after brief treatment.This publication has 9 references indexed in Scilit:
- Gonadotropin Therapy Failure Secondary to Human Chorionic Gonadotropin-Induced AntibodiesJournal of Clinical Endocrinology & Metabolism, 1981
- The Effect of Intravenously Administered Human Chorionic Gonadotrophin on Plasma Testosterone in Patients with Sexual Impotence and OligozoospermiaInternational Journal of Andrology, 1980
- Vaccines Based on the Beta-subunit of HCGPublished by Springer Nature ,1980
- Short-Term Response of Testosterone, Dihydrotestosterone, 5α- And rostane-3β, 17β-diol, Testosterone-Glucosiduronate and Estradiol-17β as Measured in the Spermatic Vein of Human Male Subjects after Infusion of GonadotropinsHormone Research, 1980
- PLASMA LEVELS OF TESTOSTERONE IN BULLSActa Endocrinologica, 1978
- Isolation of antibodies to HCG/LH from human seraNature, 1978
- Method for the determination of tracer antigen specific activity by radioimmunoassayImmunochemistry, 1974
- A METHOD FOR PRODUCING SPECIFIC ANTISERA WITH SMALL DOSES OF IMMUNOGENJournal of Clinical Endocrinology & Metabolism, 1971
- Immunoassay of Insulin: Two Antibody System: Plasma Insulin Levels of Normal, Subdiabetic and Diabetic RatsDiabetes, 1963