Validation of four definitions of melancholia by the dexamethasone suppression test
- 1 October 1984
- journal article
- research article
- Published by American Psychiatric Association Publishing in American Journal of Psychiatry
- Vol. 141 (10) , 1220-1223
- https://doi.org/10.1176/ajp.141.10.1220
Abstract
The authors evaluated four sets of diagnostic criteria, the Newcastle Index, DSM-III, RDC, and the Michigan Diagnostic Index, for the diagnosis of melancholia. Forty-nine depressed inpatients, all of whom met RDC for major depression, also received consensus diagnostic assessment for melancholia. The dexamethasone suppression test (DST) was administered before drug treatment began. Results showed that the sensitivity of the DST ranged from 39% to 48%, specificity from 80% to 100%, and diagnostic confidence from 66% to 100%. All four scales received validation, but DSM-III showed the lowest specificity and predictive value.Keywords
This publication has 9 references indexed in Scilit:
- The Newcastle Endogenous Depression Diagnostic Index: validity and reliabilityActa Psychiatrica Scandinavica, 1984
- The Melancholia Scale and the Newcastle ScalesThe British Journal of Psychiatry, 1983
- Dexamethasone Suppression Test in Depression and other Psychiatric IllnessThe British Journal of Psychiatry, 1983
- Depression and the Newcastle ScaleThe British Journal of Psychiatry, 1983
- Suicidal Behavior and the DST: Lack of AssociationAmerican Journal of Psychiatry, 1982
- Separation of Subtypes of Depression using Discriminant AnalysisThe British Journal of Psychiatry, 1982
- A Specific Laboratory Test for the Diagnosis of MelancholiaArchives of General Psychiatry, 1981
- Diagnosis of endogenous depressionJournal of Affective Disorders, 1980
- Development of a Rating Scale for Primary Depressive IllnessBritish Journal of Social and Clinical Psychology, 1967