Unidentified Factors Capable of Reducing Stress in Iodinated Protein-Fed Rats.

Abstract
A variety of natural products were examined by means of a rat-survival assay for their ability to relieve the stress induced by iodinated casein admn. Mammalian muscle and alfalfa were found to be excellent sources of the protective material(s) being measured, with liver and yeast also containing significant amts. Materials most active in the survival assay were demonstrated to reduce thymus and seminal vesicle atrophy and kidney enlargement. When low levels of iodinated protein are employed, the adrenals are also partially restored to normal by the protective substances. Under the conditions employed, the spleens are significantly larger in the protected than the unprotected animals and the testes are not reduced in size by the thyroprotein admn.
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