Malnutrition and infection in a typical rural Guatemalan Village: Lessons for the planning of preventive measures

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Abstract
A long‐term prospective study of fetal and postnatal growth and possible influences on growth was initiated in 1963 in a Guatemalan village. A high proportion of the infants were of low birth weight and they were more at risk to death in the first year of life than infants with higher birth weights. The latter also had a better chance of surviving the critical weaning period. There was a very high prevalence of infection in infancy and childhood, and a high proportion of infants with elevated cord IgM levels suggests that there had been intrauterine antigenic stimulation. Postnatal growth was generally satisfactory for the first 8–16 weeks of life but by one year the majority of the children were below the standard for height and weight, and growth continued to be unsatisfactory until the third or fourth year. There was evidence that growth was being retarded by infections and that they had their greatest effect during the second year of life. It is suggested that maternal infections are an important component of the etiology of fetal growth retardation and that planning of priorities for maternal and child health in developing countries should take this into account.

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