Deferoxamine and Sweat Iron.

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Abstract
Iron excretion in the sweat of 2 normal subjects and 4 patients with Fe overload was measured before and after injections of the Fe chelating agent, deferoxamine (DF). Baseline Fe concentrations of sweat collected from the forearm during a 1-hour exposure to moist heat were similar in all subjects (0-14 [mu]g/100 ml of sweat); after 1 g DF injected intramuscularly sweat Fe excretion was not appreciably changed (0-7 [mu]g/100 ml of sweat) despite marked increase in urinary Fe excretion in subjects with Fe overload. Deferoxamine has no appreciable effect on mobilization and excretion of Fe in sweat.

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