Effect of Megadoses of Ascorbic Acid on Serum and Urinary Oxalate
- 1 January 1980
- journal article
- research article
- Published by Elsevier in European Urology
- Vol. 6 (3) , 166-169
- https://doi.org/10.1159/000473318
Abstract
Serum and urinary oxalate was determined in 9 normal subjects, ingesting 8 g of ascorbic acid daily. Serum oxalate levels increased to 310% of control values during supplementation. Plasma ascrobate levels reached a mean value of 3.6 mg% far exceeding the previously reported plateau level of 1.8 mg%. Urinary oxalate gradually increased during ascorbate intake and 7 days post cessation of ascorbate, rose unexpectedly for all subjects into the hyperoxaluric range.Keywords
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