Effets de la Pause en Fin D’inspiration sur Ľechange gazeux et Ľhemodynamique Chez des Patients en Ventilation Mecanique
- 1 September 1977
- journal article
- research article
- Published by Springer Nature in Canadian Journal of Anesthesia/Journal canadien d'anesthésie
- Vol. 24 (5) , 550-558
- https://doi.org/10.1007/bf03005528
Abstract
Nous avons étudié les effets de la pause inspiratoire (PI) lors ďune ventilation artificielle sur ľéchange gazeux, ľhémodynamique et la distribution de la ventilation chez 13 malades atteints ďune insuffisance respiratoire aiguë. Lors de notre étude, le volume courant, le rapport inspiration/expiration et la concentration de ľoxygène inspiré ont été maintenus constants. Ľoxygénation artérielle n’a pas changé de manière significative avec la PI. Elle s’est améliorée cependant avec une pression expiratoire positive ( PEEP ). Ľespace mort physiologique ( Vd/Vt) a baissé de manière significative et cette diminution était proportionnelle à la durée de la PI. Ces résultats suggèrent que la PI entraîne des changements régionaux du rapport ventilation/perfusion produisant une diminution du Vd/Vt. Cette amélioration du rapport ventilation/perfusion ne paraît pas être suffisante pour influencer ľoxygénation ou la distribution globale de la ventilation chez ce type de malades. We have studied the effects of an inspiratory pause (PI) during artificial ventilation in 13 patients in acute respiratory insufficiency. The effects on gas exchange, haemodynamics and distribution of ventilation were observed. During the period of study the total volume, the inspiration/expiration ratio and the inspired oxygen concentration were all maintained constant. With the inspiratory pause arterial oxygenation has not changed significantly, whereas it did change favourably with PEEP. The physiological dead space (Vd/Vt) was reduced in proportion to the duration of the inspiratory pause. These results suggest that the inspiratory pause triggers regional modification of the ventilation/perfusion ratio, favouring a reduction of the Vd/Vt ratio. However, this improvement of the Vd/Vt ratio does not seem to influence the oxygenation or the total distribution of ventilation in this type of patient.This publication has 11 references indexed in Scilit:
- Effect of Mechanical Ventilation with End-inspiratory Pause on Blood-Gas ExchangeAnesthesia & Analgesia, 1976
- Mechanisms underlying vasomotor regulation of regional pulmonary blood flow in normal and disease statesThe American Journal of Medicine, 1974
- Der Einfluß eines verlängerten Inspiriums bei Beatmung wegen respiratorischer InsuffizienzThe Thoracic and Cardiovascular Surgeon, 1973
- Haemodynamic Effects of Intermittent Positive‐Pressure Ventilation With and Without an End‐Inspiratory PauseActa Anaesthesiologica Scandinavica, 1972
- VENTILATION/PERFUSION RATI0 DURING INTERMITTENT POSITIVE‐PRESSUREVENTILATIONActa Anaesthesiologica Scandinavica, 1970
- Effect of respiratory pattern on alveolar gas exchange.Journal of Applied Physiology, 1970
- Catheterization of the Heart in Man with Use of a Flow-Directed Balloon-Tipped CatheterNew England Journal of Medicine, 1970
- Effect of varying respiratory waveforms on distrubution of inspired gas during artificial ventilation.Published by Elsevier ,1969
- INFLUENCE OF FLOW PATTERN ON THE DISTRIBUTION OF RESPIRATORY AIR DURING INTERMITTENT POSITIVE-PRESSURE VENTILATIONActa Anaesthesiologica Scandinavica, 1968
- LUNG FUNCTION STUDIES. VIII. ANALYSIS OF ALVEOLAR VENTILATION BY PULMONARY N2 CLEARANCE CURVES 12Journal of Clinical Investigation, 1952