State-of-the-Art Lecture
- 1 October 1999
- journal article
- Published by Wolters Kluwer Health in Hypertension
- Vol. 34 (4) , 720-723
- https://doi.org/10.1161/01.hyp.34.4.720
Abstract
—Exercise training plays an important role in the reduction of high blood pressure. In this review, we discuss the effect of distinct intensities of exercise training on the reduction of high blood pressure in spontaneously hypertensive rats (SHR). In addition, we present some hemodynamic mechanisms and associated neural controls by which exercise training attenuates hypertension in SHR. Low-intensity exercise training is more effective in reducing high blood pressure than is high-intensity exercise training in SHR. The decrease in blood pressure is due to resting bradycardia, and in consequence, lower cardiac output. Sympathetic attenuation to the heart is the major explanation for the resting bradycardia. Recovery of the sensitivity of baroreflex control of heart rate, which is usually impaired in SHR, is an important neurogenic component involved in the benefits elicited by exercise training.Keywords
This publication has 23 references indexed in Scilit:
- Low-intensity exercise training decreases cardiac output and hypertension in spontaneously hypertensive rats.American Journal of Physiology-Heart and Circulatory Physiology, 1997
- Low-Intensity Exercise Training Attenuates Cardiac β-Adrenergic Tone During Exercise in Spontaneously Hypertensive RatsHypertension, 1995
- Prescription and Results of Physical ActivityJournal of Cardiovascular Pharmacology, 1995
- Physical training and baroreceptor control of sympathetic nerve activity in humans.Hypertension, 1994
- Antihypertensive mechanism of exerciseJournal Of Hypertension, 1993
- Effects of endurance training on baroreflex sensitivity and blood pressure in borderline hypertensionThe Lancet, 1991
- Physical exercise in the management of hypertension: a consensus statement by the World Hypertension LeagueJournal Of Hypertension, 1991
- Changes in autonomic regulation induced by physical training in mild hypertension.Hypertension, 1988
- Antihypertensive and volume-depleting effects of mild exercise on essential hypertension.Hypertension, 1987
- Influences of exercise intensity, age, and medication on resting systolic blood pressure of SHR populationsJournal of Applied Physiology, 1983