A study on the effect of ergometrine on serum prolactin levels following delivery

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Abstract
The effect of a single dose of ergometrine, 0.5 mg, with oxytocin, 5 units, (Syntometrine) given with the delivery of the anterior shoulder of the baby was compared to that of a single dose of oxytocin, 5 units, given at a similar time, monitoring the serum prolactin levels during the immediate postpartum period. A suppressant effect of Syntometrine was demonstrated, leading to the conclusion that ergometrine may have a pharmacological effect similar to bromocryptine (2-bromo-a-ergocryptine), in suppressing serum prolactin levels.