Cyclic phosphates of formycin.
- 1 January 1978
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 31 (5) , 456-467
- https://doi.org/10.7164/antibiotics.31.456
Abstract
The syntheses of N1- and N2-isopropylformycin, formycin 3'',5''-cyclic and 2'',3''-cyclic phosphate and their N-methyl and N-isopropyl derivatives are described. Substitution at N1 or N2 with a bulky alkyl group or cyclic phosphorylation of the ribose moiety made formycin resistant to adenosine deaminase.This publication has 4 references indexed in Scilit:
- Reticulol, an Inhibitor of Cyclic Nucleotide PhosphodiesterasesAgricultural and Biological Chemistry, 1977
- Some substrates and inhibitors of adenosine deaminaseBiochimica et Biophysica Acta (BBA) - Enzymology and Biological Oxidation, 1965
- ADENOSINE 3',5'-PHOSPHATE IN BIOLOGICAL MATERIALS .1. PURIFICATION AND PROPERTIES OF CYCLIC 3',5'-NUCLEOTIDE PHOSPHODIESTERASE AND USE SF THIS ENZYME TO CHARACTERIZE ADENOSINE 3',5'-PHOSPHATE IN HUMAN URINE1962
- FRACTIONATION AND CHARACTERIZATION OF A CYCLIC ADENINE RIBONUCLEOTIDE FORMED BY TISSUE PARTICLESJournal of Biological Chemistry, 1958