Influence of Cyclopropenoid Fatty Acids on the Cholesterol Metabolism of Cockerels

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Abstract
Cyclopropenoid fatty acids, as in Sterculia foetida oil and cottonseed oil, were fed to White Leghorn cockerels to determine whether these acids altered cholesterol metabolism. Corn oil was fed as a control. These cyclopropenoid fatty acids were found to cause increased plasma cholesterol, aortic atherosclerosis, liver weight, volume of bile in the gallbladder, bile acids in the bile, and bile acid excretion. The liver cholesterol concentration of the test cockerels was less than that of the controls. There was no difference in sterol retention, weight gain, or feed efficiency.