Identification of Antigenic Proteins of Setaria Cervi by Immunoblotting Technique
- 31 December 1986
- journal article
- research article
- Published by Taylor & Francis in Immunological Investigations
- Vol. 16 (2) , 139-149
- https://doi.org/10.3109/08820138709030571
Abstract
Identification and characterization of antigenic proteins of Setaria cervi (bovine filarial parasite) adults and microfilariae was done by immunoblotting technique using hyperimmune rabbit sera against S. cervi and Brugia malayi. The antigens recognized by these sera were detected by using 125Iprotein-A followed by autoradiography. Fifteen different antigens were observed to be common between adult and microfilarial stages of the parasite. Some stage specific antigens were also identified. Many antigens of S. cervi adults and microfilariae were also recognized by rabbit anti-B. malayi serum showing the existence of common antigenic determinants between the bovine and human filarial parasites.Keywords
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