The Metabolic Fate of Dietary 1-[14C]Linoleate and 1-[14C]Palmitate in Meal-Fed Rats

Abstract
The relative rates of oxidation to respiratory 14CO2 of dietary 1-[14C]linoleate and 1-[14C]palmitate in rats fed a single meal containing the labeled fatty acids were investigated. The oxidation of dietary linoleate and palmitate, expressed as a fraction of the radioactivity absorbed, occurred at similar rates. Significantly more [14C]linoleate than [14C]palmitate accumulated in the livers of the rats and accumulation of label in hepatic phospholipids was greater when [14C]linoleate was fed than when [14C]palmitate was fed.