Studies on mycotrienin antibiotics, a novel class of ansamycins. III. The isolation, characterization and structures of mycotrienols I and II.
- 1 January 1982
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 35 (11) , 1474-1479
- https://doi.org/10.7164/antibiotics.35.1474
Abstract
Two minor components designated mycotrienols I and II, which were concurrently produced with mycotrienins I and II by Streptomyces rishiriensis T-23, were isolated and characterized. Like mycotrienins I and II, mycotrienols I and II are also interconvertible via redox reaction, and their structures were established, as depicted in 3 and 4, on the basis of 13C NMR evidence, along with chemical degradation. The biological activities are discussed.This publication has 3 references indexed in Scilit:
- Studies on mycotrienin antibiotics, a novel class of ansamycins. II. Structure elucidation and biosynthesis of mycotrienins I and II.The Journal of Antibiotics, 1982
- Studies on mycotrienin antibiotics, a novel class of ansamycins. I. Taxonomy, fermentation, isolation and properties of mycotrienins I and II.The Journal of Antibiotics, 1982
- Tumor inhibitors. 124. Structural requirements for antileukemic activity among the naturally occurring and semisynthetic maytansinoidsJournal of Medicinal Chemistry, 1978