Rapid Emergence of Resistance to Linezolid during Linezolid Therapy of an Enterococcus faecium Infection
- 1 December 2006
- journal article
- case report
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 50 (12) , 4217-4219
- https://doi.org/10.1128/aac.00518-06
Abstract
We report the emergence of linezolid resistance (MICs of 16 to 32 mg/liter) in clonally related vancomycin-susceptible and -resistant Enterococcus faecium isolates from an intensive care unit patient after 12 days of linezolid therapy. Only linezolid-susceptible isolates of the same clone were detected at 28 days after termination of linezolid therapy.Keywords
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