Fungicidal Monoclonal Antibody C7 Binds to Candida albicans Als3
- 1 July 2007
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 75 (7) , 3680-3682
- https://doi.org/10.1128/iai.01840-06
Abstract
Monoclonal antibody (MAb) C7 reacted with a >200-kDa component from the Candida albicans cell wall identified by matrix-assisted laser desorption ionization-time-of-flight mass spectrometry as Als3. It also bound the recombinant N terminus of Als3. Binding of MAb C7 to Als3 may explain the biological activities exerted by the MAb on C. albicans .Keywords
This publication has 10 references indexed in Scilit:
- Diagnosis of invasive candidiasis by enzyme-linked immunosorbent assay using the N-terminal fragment of Candida albicans hyphal wall protein 1BMC Microbiology, 2007
- A Fungicidal Monoclonal Antibody Protects against Murine Invasive CandidiasisInfection and Immunity, 2006
- The Anti- Candida albicans Vaccine Composed of the Recombinant N Terminus of Als1p Reduces Fungal Burden and Improves Survival in Both Immunocompetent and Immunocompromised MiceInfection and Immunity, 2005
- Antifungal and Antitumor Activities of a Monoclonal Antibody Directed Against a Stress Mannoprotein of Candida albicansCurrent Molecular Medicine, 2005
- Functional analysis of the Candida albicans ALS1 gene productYeast, 2004
- A Monoclonal Antibody Directed against aCandida albicansCell Wall Mannoprotein Exerts Three Anti-C. albicansActivitiesInfection and Immunity, 2003
- The ALS gene family of Candida albicansTrends in Microbiology, 2001
- Identification of Candida albicans ALS2 and ALS4 and Localization of Als Proteins to the Fungal Cell SurfaceJournal of Bacteriology, 1998
- Heat-shock mannoproteins as targets of secretory IgA in Candida albicans.1994
- Heat-Shock Mannoproteins as Targets of Secretory IgA in Candida albicansThe Journal of Infectious Diseases, 1994