Polychlorinated dibenzo‐p‐dioxins (PCDDS) and polychlorinated dibenzofurans (PCDFS) in human milk samples collected across Canada in 1986–87
- 1 July 1993
- journal article
- research article
- Published by Taylor & Francis in Food Additives & Contaminants
- Vol. 10 (4) , 419-428
- https://doi.org/10.1080/02652039309374165
Abstract
Monitoring of human milk samples for the presence of chemical contaminants has been carried out in Canada for several decades. In 1986–87 over 400 donations of human milk were collected nationwide and 100 of these, selected by province according to population, were analysed for the PCDDs/PCDFs. The results show the presence of about eleven different analytes all with 2,3,7,8‐substitution with the PCDDs at higher and more variable concentrations than the PCDFs. On a 2,3,7,8‐TCDD toxic equivalents (TEQ) basis, the mean value for the country is about 15 ng per kg milk fat. This TEQ value is similar to that from many other industrialized nations and about 50% lower than certain European states. Little or no variation was apparent in the milk content among the various Canadian provinces probably reflecting the uniformity of the general food supply across the country. Limited data over a period of five years suggest the average level of these compounds in human milk may be decreasing.Keywords
This publication has 9 references indexed in Scilit:
- Levels of chlorinated hydrocarbon residues in Canadian human breast milk and their relationship to some characteristics of the donorsFood Additives & Contaminants, 1993
- Trend studies of polychlorinated biphenyls, dibenzo-p-dioxins and dibenzofurans in human milkChemosphere, 1991
- PCDDs, PCDFs and PCBs in human milk of women exposed to a PCB fire and of women from the general population of the province of Québec - CanadaChemosphere, 1991
- Gas chromatographic separations of all 136 tetra- to octapolychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans on nine different stationary phasesJournal of Chromatography A, 1991
- Polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) in cows' milk packaged in plastic-coated bleached paperboard containersJournal of Agricultural and Food Chemistry, 1991
- The international toxicity equivalency factor (I-TEF) method of risk assessment for complex mixtures of dioxins and related compoundsChemosphere, 1990
- Background levels in humansPublished by Elsevier ,1989
- WHO coordinated intercountry studies on levels of PCDDs and PCDFs in human milkChemosphere, 1989
- Levels and trends of chlorinated hydrocarbon contaminants in the breast milk of Canadian womenFood Additives & Contaminants: Part A, 1986