Genetic testing for Alzheimerʼs disease: how close is reality?
- 1 July 1999
- journal article
- review article
- Published by Wolters Kluwer Health in Current Opinion in Psychiatry
- Vol. 12 (4) , 487-493
- https://doi.org/10.1097/00001504-199907000-00019
Abstract
No abstract availableKeywords
This publication has 100 references indexed in Scilit:
- Genetic association of two chromosome 14 genes (presenilin 1 and α1‐Antichymotrypsin) with Alzheimer's diseaseAnnals of Neurology, 1998
- Additive Effects of PS1 and APP Mutations on Secretion of the 42-Residue Amyloid β-ProteinNeurobiology of Disease, 1998
- α2‐Macroglobulin Attenuates β‐Amyloid Peptide 1–40 Fibril Formation and Associated Neurotoxicity of Cultured Fetal Rat Cortical NeuronsJournal of Neurochemistry, 1998
- A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementiaNature Genetics, 1998
- Multiple, diverse senile plaque–associated proteins are ligands of an apolipoprotein e receptor, the α2‐macroglobulin receptor/low‐density‐lipoprotein receptor—related proteinAnnals of Neurology, 1995
- Increased β‐amyloid release and levels of amyloid precursor protein (APP) in fibroblast cell lines from family members with the Swedish Alzheimer's disease APP670/671 mutationFEBS Letters, 1994
- Biochemical Evidence for the Long-Tail Form (Aβ1-42/43) of Amyloid β Protein as a Seed Molecule in Cerebral Deposits of Alzheimer′s DiseaseBiochemical and Biophysical Research Communications, 1994
- Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset FamiliesScience, 1993
- Mapping of a gene predisposing to early–onset Alzheimer's disease to chromosome 14q24.3Nature Genetics, 1992
- Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's diseaseNature, 1991