Gas Chromatography: A New Industrial Process of Separation. Application to Essential Oils

Abstract
Originally, chromatography was designed as a preparative technique for biological organic chemistry (1). Liquid chromatography was the preferred method, and people used a vertical column filled with silica or alumina through which a carrier liquid was percolated. The output liquid or eluent was collected in many different fractions which were then analyzed, concentrated, and used as needed. The weight of the vertical column of liquid was the only driving force which drastically limited the separation power and the productivity of the technique (2)