Biomarkers of oh Radical DamageIn Vivo
- 1 January 1991
- journal article
- research article
- Published by Taylor & Francis in Free Radical Research Communications
- Vol. 12 (1) , 11-16
- https://doi.org/10.3109/10715769109145762
Abstract
Mechanisms of formation of o-tyrosine (o-Tyr) and thymine glycol (TG), the two possible markers of OH radical generation in biosystems and in vivo are described. The o-Tyr measurements require invasivc approaches, while TG detection may be accomplished by noninvasive analysis in the urine.Keywords
This publication has 15 references indexed in Scilit:
- Generation of oxy radicals in biosystemsMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1989
- Critical Review of rate constants for reactions of hydrated electrons, hydrogen atoms and hydroxyl radicals (⋅OH/⋅O− in Aqueous SolutionJournal of Physical and Chemical Reference Data, 1988
- Oxygen Radicals in Biology and MedicinePublished by Springer Nature ,1988
- In vivo studies on the formation of m-tyrosine and o-tyrosine from L-phenylalanine in rats.CHEMICAL & PHARMACEUTICAL BULLETIN, 1986
- Studies on the hydroxylation of phenylalanine by 6,7-dimethyl-5,6,7,8-tetrahydropteridine.CHEMICAL & PHARMACEUTICAL BULLETIN, 1984
- Hydroxylation of phenylalanine by the hypoxanthine-xanthine oxidase system.CHEMICAL & PHARMACEUTICAL BULLETIN, 1984
- OH Radical-induced Products of Tyrosine PeptidesInternational Journal of Radiation Biology, 1984
- Fifteen-minute acid hydrolysis of peptidesAnalytical Biochemistry, 1974
- Chemical Effects of Ionizing RadiationsNature, 1948
- ber die Katalyse des HydroperoxydesThe Science of Nature, 1932