Saturated heterocycles, part 161 [1]. Synthesis of 2‐hydroxycycloalkyl‐substituted 1,3,4‐oxadiazoles, 1,3,4‐thiadiazoles and 1,2,4‐triazoles
- 1 May 1990
- journal article
- research article
- Published by Wiley in Journal of Heterocyclic Chemistry
- Vol. 27 (4) , 951-955
- https://doi.org/10.1002/jhet.5570270424
Abstract
A number of 2‐hydroxycycloalkyl‐substituted 1,3,4‐oxadiazole, 1,3,4‐thiadiazole and 1,2,4‐triazole derivatives were prepared by different methods from cis‐ and trans‐2‐hydroxy‐1‐cycloalkanecarbohydrazides and their isocyanate or isothiocyanate adducts. In contrast with the related ring‐closure reactions of 2‐aminobenzoylhydrazides, no condensed skeleton heterocycles were formed in this case.Keywords
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