Beta-Thalassaemia and Some Rare Haemoglobin Variants in the Highlands of Scotland

Abstract
A survey is described of 3968 individuals in the northern and western highlands of Scotland for haemoglobinopathies. Twenty-three abnormalities were found, involving 17 cases of beta-thalassaemia minor, 3 of Haemoglobin Koln, one man with Haemoglobin Lepore, and one case with Haemoglobin Hopkins 2. An infant with multiple birth abnormalities had a persistent high foetal haemoglobin. No examples of glucose-6-phosphate dehydrogenase deficiency of the red cells were discovered.