Deoxyribonucleic Acid Base Compositions of Dermatophytes

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Abstract
DNA was extracted and purified from 555 dermatophyte isolates representing 34 spp. of Trichophyton, Microsporum and Epidermophyton. The base compositions of the chromosomal DNA were determined by CsCl density gradient centrifugation and were in the narrow range of 48.7-50.3 mol% G + C. A satellite DNA component assumed to be of mitochondrial origin was present in most strains, with a G + C content ranging from 14.7-30.8 mol% G + C. Heterogeneity in microscopic and colonial characteristics was not reflected in differences in the mean G + C content of the chromosomal DNA. Strains varied in the G + C contents of satellite DNA, but these did not correlate with traditional species concepts.