Long-Range Correlation and Partial 1/ f α Spectrum in a Noncoding DNA Sequence
- 7 February 1992
- journal article
- Published by IOP Publishing in Europhysics Letters
- Vol. 17 (7) , 655-660
- https://doi.org/10.1209/0295-5075/17/7/014
Abstract
Mutual information function, which is an alternative to correlation function for symbolic sequences, and a "symbolic spectrum" are calculated for a human DNA sequence containing mostly intron segments, those that do not code for proteins. It is observed that the mutual information function of this sequence decays very slowly, and the correlation length is extremely long (at least 800 bases). The symbolic spectrum of the sequence at very low frequencies can be approximated by 1/fα, where f is the frequency and α ranges from 0.5 to 0.85. It is suggested that the existence of the repetitive patterns in the sequence is mainly responsible for the observed long-range correlation. A possible connection between this long-range correlation and those in music notes is also briefly discussed.Keywords
This publication has 19 references indexed in Scilit:
- Expansion-modification systems: A model for spatial 1/fspectraPhysical Review A, 1991
- Spatial 1/fSpectra in Open Dynamical SystemsEurophysics Letters, 1989
- The human factor VII gene is polymorphic due to variation in repeat copy number in a minisatelliteGene, 1988
- Nucleotide sequence of the gene coding for human factor VII, a vitamin K-dependent protein participating in blood coagulation.Proceedings of the National Academy of Sciences, 1987
- Recognition of protein coding regions in DNA sequencesNucleic Acids Research, 1982
- Repetitive Sequences in Eukaryotic DNA and their ExpressionAnnual Review of Biochemistry, 1982
- Repeated Genes in EukaryotesAnnual Review of Biochemistry, 1980
- Repeated Segments of DNAScientific American, 1970
- Evolution by Gene DuplicationPublished by Springer Nature ,1970
- Repeated Sequences in DNAScience, 1968