Jaundice associated with naproxen
Open Access
- 1 May 1980
- journal article
- case report
- Published by Oxford University Press (OUP)
- Vol. 56 (655) , 368-370
- https://doi.org/10.1136/pgmj.56.655.368
Abstract
Summary: Hepatic injury in association with naproxen therapy is described and documented by liver biopsy in one patient. Histological findings were consistent with a drug-induced hepatitis, and cessation of therapy led to reversal of the clinical and biochemical changes. Circumstantial evidence is in favour of a hypersensitivity response to the drug rather than direct hepatotoxicity. Increased awareness of clinicians of this probably rare side effect of naproxen may help prompt identification of similar cases.Keywords
This publication has 5 references indexed in Scilit:
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- Pharmacokinetics of naproxen overdosesClinical Pharmacology & Therapeutics, 1976
- JAUNDICE ASSOCIATED WITH NAPROXENThe Lancet, 1974
- Klinische Untersuchung Von Naproxen, Vor Allem Mit Bezug Auf Seine VerträglichkeitScandinavian Journal of Rheumatology, 1973