In Vitro Activity of OPT-80 Tested against Clinical Isolates of Toxin-Producing Clostridium difficile
- 1 November 2008
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 52 (11) , 4163-4165
- https://doi.org/10.1128/aac.00476-08
Abstract
Agar dilution antimicrobial susceptibility testing (CLSI, M11-A7, 2007) performed for 208 toxin-producing clinical isolates of Clostridium difficile resulted in OPT-80 MICs ranging from 0.06 to 1 microg/ml, with 90% of the isolates inhibited by a concentration of 0.5 microg/ml. The in vitro activity of OPT-80 was independent of the susceptibilities of isolates to nine other antimicrobial agents.Keywords
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