Homochiral fluoro-organic compounds. Synthesis of the two enantiomers of (Z)-3-fluoro-4-phenyl-1-(p-tolylsulphonyl)but-3-en-2-ol through microbial reduction
- 1 January 1990
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 3,p. 579-583
- https://doi.org/10.1039/p19900000579
Abstract
The reduction of (Z)-3-fluoro-4-phenyl-1-(p-tolylsulphonyl)but-3-en-2-one with growing cultures of Geotrichum candidum and Phanerochaete chrysosporium afforded (S)- and (R)-3-fluoro-4-phenyl-1-(p-tolylsulphonyl)but-3-en-2-ol in enantiomerically pure form.This publication has 4 references indexed in Scilit:
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- Production of (R)-1-(1,3-dithian-2-yl)propan-2-ol by microbial reductionJournal of the Chemical Society, Perkin Transactions 1, 1986
- Microbiological reduction of .alpha.,.beta.-unsaturated ketones by Beauveria sulfurescensThe Journal of Organic Chemistry, 1982