Some Effects of Feeding Various Filled Milks to Dairy Calves. IV. Necropsy Findings, Electrocardiographic Studies, and Creatinuria Ratios

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Abstract
Gross and microscopic lesions were found in the cardiac and skeletal muscles of calves fed corn oil or lard filled milk. Similar lesions were demonstrated in animals receiving butter oil prepared from oxidized butter. Both oral and intramuscular supplementation of the corn oil and lard diets with high levels of tocopherol prevented muscular lesions. No evidence of muscular involvement was encountered in calves fed a low-fat, tocopherol-poor ration. The microscopic lesions are characterized in detail. Marked changes occurred in the electrographic pattern of calves fed corn oil filled milk. Creatinuria ratios did not provide a means of following the development of muscular involvement.