Effects of the virulence plasmid ColV, I-K94 on the sensitivity ofEscherichia coli to putative environmental inhibitory agents

Abstract
Summary Derivatives ofEscherichia coli carrying the virulence plasmid, ColV, I-K94 were more resistant than the ColV parents to phage Mel but were more sensitive to the hydrophobic inhibitors deoxycholate, erythromycin and lysozyme. The basis for these changes in sensitivity has been examined in ColV+ mutants with altered colicin or VmpA protein levels and in ColV+ strains with repressed transfer properties.