I-131 METAIODOBENZYLGUANIDINE SCINTIGRAPHY FOR THE LOCATION OF NEURO-BLASTOMA - PRELIMINARY EXPERIENCE IN 10 CASES

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  • 1 January 1985
    • journal article
    • research article
    • Vol. 26  (7) , 736-742
Abstract
Ten patients with histologically proven neuroblastoma were studied by [131I]MIBG [metaiodobenzylguanidine] scintigraphy. Tumor uptake of the radiopharmaceutical showed a spectrum varying from no uptake to 1 case, to slight uptake in 2, moderate uptake in 2 and intense uptake in 5 cases. [131I]MIBG scintigraphy was more effective in demonstrating the extent of neuroblastoma spread than were conventional bone scan and CT [computed tomography] in 1 patient, equal to these modalities in 4 cases, almost equal in 2 cases and significantly inferior in 3 cases. [131I]MIBG scintigraphy is useful in detecting the presence and delineating the distribution of neuroblastoma and may, in certain cases, have therapeutic potential.