RELATIONSHIP BETWEEN “CHLORAMPHENICOL REDUCTASE ACTIVITY” AND CHLORAMPHENICOL RESISTANCE IN ESCHERICHIA COLI,

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Abstract
High concns. of glucose in "N-free" media are inhibitory to the "chloramphenicol reductase activity" of resistant cultures. A direct correlation has been shown between chloramphenicol resistance and "chloramphenicol reductase activity" in E. coli at certain stages of resistance; however, this activity does not seem to account for all of the resistance which can be developed.