The human genes for complement components 6 (C6) and 9 (C9) are closely linked on chromosome 5.
Open Access
- 1 September 1991
- journal article
- research article
- Published by BMJ in Journal of Medical Genetics
- Vol. 28 (9) , 587-590
- https://doi.org/10.1136/jmg.28.9.587
Abstract
We have used a cDNA probe for human complement component 9 (C9), which detects three DNA polymorphisms, to analyse the inheritance of C9 in families informative for C6 protein variants. We found that these genes are closely linked with a lod score of 9.28 at recombination fraction 0.00. There is not indication of allelic association.Keywords
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