Abstract
This year marks the 50th anniversary of the awarding of the Nobel Prize in Physiology and Medicine to Kendall, Hench, and Reichstein for the isolation and characterization of adrenocorticotrophic hormones.1 Until now, nothing has even begun to approach the dramatic effect glucocorticoids have had in improving the care of patients with rheumatoid arthritis and other systemic inflammatory diseases and creating optimism in the arthritis community. Products devised by the biotechnology industry for the treatment of rheumatoid arthritis have now been introduced into the clinic and appear to have ushered in a new era of scientifically based therapy for arthritis. Products . . .