Radioiron Citrate as Tracer to Determine Disappearance Rate of Plasma Iron in Normal Subjects.

Abstract
Radioiron turnover studies can be performed using radioiron citrate as the injected tracer, rather than protein bound radioiron, at least in patients with adequate residual Fe binding capacity. The transfer of the radioiron from citrate to protein in vivo is rapid and complete. Plasma volume and plasma Fe disappearance rate values, detd. in 6 patients, were identical when radioiron citrate was injected directly into the normal subjects or when plasma was incubated with radioiron citrate.